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Review Article OPEN ACCESS Dongjie Wu 1,# , Qingjuan Wu 1 , Yanxuan Wu 2 , Ziwei Guo 1 , Li Wang 1 , Yi Wang 1,3 , Qian Zeng 4 , Liang Shi 2 , Bin Shi 2 , Gongchang Yu 2,* and Wenliang Lv 1,* Received: Revised: Accepted: Published online: Author information Citation: Zhang H, Wu D, Wu Q, Wu Y, Guo Z, Wang L, et al

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Since higher levels of conventional antimicrobials are required to combat biofilm infections, the risk of systemic toxicity also rises